The Wexford Montego Bay is located on the southern edge of the Hip Strip stretch of shopping, dining, and night life. The hotel is within five minutes walk of the world famous Doctors Cave Beach to the right and the Aquasol Beach to the left. The Sangster International Airport is around 1.5 kilometres away from the hotel.

From the airport, Its take approximately 5 minutes driving time to the hotel. Nearby place of interest include Aqua Salt water sports park (about 500 metres), Jimmy's Buffet Maragaritaville (about 500 metres), Coral Cliff Casino (about 500 metres), Central Montego Bay and Bay West shopping mall (about 1.2 kilometres) and Rose Hall Great House (about 10 kilometres).