Somerset Salcedo is ideally located in the central of Manila's business, shopping, entertainment and dining districts along Makati Avenue, Sen. Gil Puyat and Ayala Avenues make it a popular choice for travellers. A few locations just minutes away are Philippines Stock Exchange, Citibank Tower, The Enterprise Centre, Glorietta malls, Buendia MRT Station, PBCom Tower, Philam Life Tower, Salcedo Park and Saturday Market.

Nearby attractions around Somerset Salcedo includes Ayala Centre, Ayala Museum, Makati Avenue, Manila Bay and SM Mega Mall. Ninoy Aquino International Airport is just 30 minutes drive from the hotel.