To go to Pedregal Palace Hotel Mexico City from the airport take Circuito Interior, take Rio Churubusco then Insurgentes Sur and Periferico all the way to the Luis Cabrera Bridge.
From the South going North take Periferico Sur towards the bridge in front of Angeles Hospital, right lane on Periferico up to the Luis Cabrera Bridge.
From the North going South take Periferico up to San Jeronimo, right lane on Periferico up to the Luis Cabrera Bridge.