The Oberoi Mumbai Hotel is centrally located in Nariman Point, the main financial district of Mumbai, with the Bombay Stock Exchange, The Legislative Assembly (Mantralaya) and most international and national banks headquartered within a 1 kilometre radius.

In addition to being the financial capital of India, Mumbai is also known for 'Bollywood' (the term affectionately derived from Bombay's Hollywood) - its thriving film industry. Most architectural landmarks, vestiges of the British Era, are situated within walking distance of the hotel. The hotel overlooks the Arabian Sea and has a spectacular view of the city’s main promenade Marine Drive, also known as the Queen’s Necklace.