Oasis Hotel Guangzhou is located at the East end of Haizhu's Xinjiao Road. Surrounded by the waters of the Pearl River, Haizhu District in Guangzhou City is rich in infrastructure, having 14 bridges and two Metro lines linking it to the rest of the city. The district is also known for upscale real estate and some of the most expensive hotels in Guangzhou.

Among the business hotels in Guangzhou, the Oasis Hotel Guangzhou is the one nearest to Pazhou Complex, home of the Canton Fair. The Huacheng International Exhibition Center is only a 10 minute drive from the hotel. Sun Yat Sen University, Guangzhou Airport and a vast orchard are nearby as well.