Hyatt Hotel & Casino Manila is right at the heart of Manila's business, shopping and entertainment areas. Access to the domestic and international airport terminals is less than 30 minutes by private transport. The port terminal, a more leisurely way to reach the country's neighbouring islands, is less than ten minutes away from the hotel. The hotel is located around 2 km from South Harbor.

You can reach the hotel from Manila International Airport and Manila Domestic Airport in 30 minutes by car,5 minutes driving from railway station, 30 minutes by car from Makati City Business District and by walking distance from Downtown Manila.