Ascott Hotel Makati located in Glorietta 4, Ayala Centre is in the heart of Makati City's central business and entertainment district. Ascott Hotel Makati's serviced apartments offer convenience for both business and recreation. Trains and jeepneys are available for destinations throughout Makati.

The Ninoy Aquino International Airport (NAIA) Terminal 1 serves the general area of Manila and its surrounding metropolitan venues. Approximately 45 minutes away from Ascott Hotel Makati, it is the main international gateway for travellers to the Philippines and the hub for international carriers.

Nearby attractions around the hotel includes Ayala Centre, Ayala Museum, Makati Avenue and Manila Bay. Ninoy Aquino International Airport is just around 30 minutes drive from the Ascott Hotel Makati.